Montepulciano, almost 2 hours by bus from Siena is built along a narrow ridge some 600 m above sea level. The town was designed by Antonio da Sangallo the Elder for Cosimo I. The steep and narrow streets are crammed with Renaissance palazzi and churches. The town is best known for its Vino Nobile wines. The long and winding Corso climbs to the main square a perfect place to sample this tasty wine with some tasty nibbles and good company.